OPRM1, opioid receptor mu 1, 4988

N. diseases: 370; N. variants: 42
Source: ALL
Variant DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Disease Disease Class Score vda EI vda N. PMIDs First Ref. Last Ref.
dbSNP: rs1799971
rs1799971 		0.559 0.600 6 154039662 missense variant A/G snv 0.19 0.12
CUI: C0524662
Disease: Opiate Addiction
Opiate Addiction 		Chemically-Induced Disorders; Mental Disorders 0.100 0.900 10 2001 2020
dbSNP: rs1799971
rs1799971 		0.559 0.600 6 154039662 missense variant A/G snv 0.19 0.12
CUI: C0030193
Disease: Pain
Pain 		Pathological Conditions, Signs and Symptoms 0.100 0.979 47 2004 2019
dbSNP: rs1799971
rs1799971 		0.559 0.600 6 154039662 missense variant A/G snv 0.19 0.12
CUI: C0001973
Disease: Alcoholic Intoxication, Chronic
Alcoholic Intoxication, Chronic 		Chemically-Induced Disorders; Mental Disorders 0.100 0.893 28 1998 2019
dbSNP: rs1799971
rs1799971 		0.559 0.600 6 154039662 missense variant A/G snv 0.19 0.12
CUI: C0563625
Disease: Agnosia for Pain
Agnosia for Pain 		Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms 0.100 0.944 18 2006 2019
dbSNP: rs1799971
rs1799971 		0.559 0.600 6 154039662 missense variant A/G snv 0.19 0.12
CUI: C0085281
Disease: Addictive Behavior
Addictive Behavior 		Behavior and Behavior Mechanisms 0.090 1.000 9 2004 2019
dbSNP: rs1799971
rs1799971 		0.559 0.600 6 154039662 missense variant A/G snv 0.19 0.12
CUI: C0030201
Disease: Pain, Postoperative
Pain, Postoperative 		Pathological Conditions, Signs and Symptoms 0.070 0.857 7 2006 2019
dbSNP: rs1799971
rs1799971 		0.559 0.600 6 154039662 missense variant A/G snv 0.19 0.12
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		Mental Disorders 0.040 0.750 4 2010 2019
dbSNP: rs1799971
rs1799971 		0.559 0.600 6 154039662 missense variant A/G snv 0.19 0.12
CUI: C0596240
Disease: Cancer Pain
Cancer Pain 		Pathological Conditions, Signs and Symptoms 0.030 1.000 3 2013 2019
dbSNP: rs1799971
rs1799971 		0.559 0.600 6 154039662 missense variant A/G snv 0.19 0.12
CUI: C0027498
Disease: Nausea and vomiting
Nausea and vomiting 		Pathological Conditions, Signs and Symptoms 0.030 0.667 3 2011 2019
dbSNP: rs1799971
rs1799971 		0.559 0.600 6 154039662 missense variant A/G snv 0.19 0.12
CUI: C0013146
Disease: Drug abuse
Drug abuse 		Chemically-Induced Disorders; Mental Disorders 0.020 1.000 2 2019 2019
dbSNP: rs1323040
rs1323040 		0.882 0.080 6 154010889 5 prime UTR variant A/G snv 2.1E-05
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung 		Neoplasms; Respiratory Tract Diseases 0.010 1.000 1 2019 2019
dbSNP: rs1323040
rs1323040 		0.882 0.080 6 154010889 5 prime UTR variant A/G snv 2.1E-05
CUI: C1306460
Disease: Primary malignant neoplasm of lung
Primary malignant neoplasm of lung 		Neoplasms; Respiratory Tract Diseases 0.010 1.000 1 2019 2019
dbSNP: rs1323040
rs1323040 		0.882 0.080 6 154010889 5 prime UTR variant A/G snv 2.1E-05
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		Neoplasms; Respiratory Tract Diseases 0.010 1.000 1 2019 2019
dbSNP: rs1799971
rs1799971 		0.559 0.600 6 154039662 missense variant A/G snv 0.19 0.12
CUI: C0278139
Disease: Moderate pain
Moderate pain 		Pathological Conditions, Signs and Symptoms 0.010 1.000 1 2019 2019
dbSNP: rs1799971
rs1799971 		0.559 0.600 6 154039662 missense variant A/G snv 0.19 0.12
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		Neoplasms; Respiratory Tract Diseases 0.010 1.000 1 2019 2019
dbSNP: rs1799971
rs1799971 		0.559 0.600 6 154039662 missense variant A/G snv 0.19 0.12
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder 		Mental Disorders 0.010 1.000 1 2019 2019
dbSNP: rs1799971
rs1799971 		0.559 0.600 6 154039662 missense variant A/G snv 0.19 0.12
CUI: C0001957
Disease: Alcohol Withdrawal Delirium
Alcohol Withdrawal Delirium 		Nervous System Diseases; Chemically-Induced Disorders; Mental Disorders 0.010 1.000 1 2019 2019
dbSNP: rs1799971
rs1799971 		0.559 0.600 6 154039662 missense variant A/G snv 0.19 0.12
CUI: C0338908
Disease: Mixed anxiety and depressive disorder
Mixed anxiety and depressive disorder 		Mental Disorders 0.010 1.000 1 2019 2019
dbSNP: rs1799971
rs1799971 		0.559 0.600 6 154039662 missense variant A/G snv 0.19 0.12
CUI: C0438696
Disease: Suicidal
Suicidal 		Behavior and Behavior Mechanisms 0.010 1.000 1 2019 2019
dbSNP: rs1799971
rs1799971 		0.559 0.600 6 154039662 missense variant A/G snv 0.19 0.12
CUI: C1611743
Disease: Familial (FPAH)
Familial (FPAH) 		0.010 1.000 1 2019 2019
dbSNP: rs1799971
rs1799971 		0.559 0.600 6 154039662 missense variant A/G snv 0.19 0.12
CUI: C0030662
Disease: Gambling, Pathological
Gambling, Pathological 		Mental Disorders; Behavior and Behavior Mechanisms 0.010 1.000 1 2019 2019
dbSNP: rs1799971
rs1799971 		0.559 0.600 6 154039662 missense variant A/G snv 0.19 0.12
CUI: C0687132
Disease: heavy drinking
heavy drinking 		0.010 1.000 1 2019 2019
dbSNP: rs1799971
rs1799971 		0.559 0.600 6 154039662 missense variant A/G snv 0.19 0.12
CUI: C1306460
Disease: Primary malignant neoplasm of lung
Primary malignant neoplasm of lung 		Neoplasms; Respiratory Tract Diseases 0.010 1.000 1 2019 2019
dbSNP: rs1799971
rs1799971 		0.559 0.600 6 154039662 missense variant A/G snv 0.19 0.12
CUI: C0033860
Disease: Psoriasis
Psoriasis 		Skin and Connective Tissue Diseases 0.010 1.000 1 2019 2019
dbSNP: rs1799971
rs1799971 		0.559 0.600 6 154039662 missense variant A/G snv 0.19 0.12
CUI: C0520679
Disease: Sleep Apnea, Obstructive
Sleep Apnea, Obstructive 		Respiratory Tract Diseases; Nervous System Diseases 0.010 1.000 1 2019 2019